Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218145 | 0.87 | ADRB1 (0.43) | MEN1GAAKMT2AAPPTDP1 | |
| SCHEMBL5350831 | 0.85 | MEN1 (0.47) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL6237655 | 0.84 | CTSS (0.45) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL29112424 | 0.83 | MEN1 (0.48) | MEN1GAAKMT2AIDO1TDP1 | |
| SCHEMBL30334063 | 0.83 | DRD2 (0.49) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL30334617 | 0.83 | DRD2 (0.49) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL3650901 | 0.83 | DRD2 (0.49) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL10318009 | 0.81 | KDM4E (0.46) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL24298860 | 0.80 | MEN1 (0.46) | MEN1GAAKMT2AMALT1IDO1 | |
| SCHEMBL19331769 | 0.80 | FPR3 (0.47) | MEN1GAAKMT2AMALT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076017-A1 | CARBAMATES FOR USE AS SARM1 INHIBITORS | GENENTECH, INC. (US) | 2025-04-10 | — | — | WO | disclosed |