SCHEMBL29112554

SCHEMBL29112554

O=C(OO)c1ccc(C(=O)OO)cc1.[MgH2]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
F2 P00734 1/20 0.43
LMNA P02545 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
PTPN1 P18031 1/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286650 0.97 CES2 (0.48) CES2CES1CA1CA2CA12
SCHEMBL11880655 0.94 CES2 (0.46) CES2CES1CA1CA2CA12
SCHEMBL28597958 0.94 CES2 (0.46) CES2CES1CA1CA2CA12
Ethylene SCHEMBL1366416 0.91 CES2 (0.43) CES2CES1CA1CA2CA12
SCHEMBL27500596 0.89 TSHR (0.60) CES2CES1CA1CA2CA12
SCHEMBL248548 0.88 CES2 (0.62) CES2CES1CA1CA2NPC1
Cyclopropane SCHEMBL18860160 0.88 KDM4E (0.42) CES2CES1CA1CA2CA12
SCHEMBL3876168 0.88 BCL2L1 (0.52) CES2CES1CA1CA2CA12
SCHEMBL247945 0.86 CA1 (0.62) CES2CA1CA2CA12CA7
SCHEMBL1286652 0.86 TSHR (0.63) CES2CES1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829611-A Reduction of monomeric isocyanates by porous materials 巴斯夫欧洲公司 2023-09-29 CN disclosed