SCHEMBL248548

SCHEMBL248548

O=C(OO)c1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.62
CES1 P23141 1/20 0.62
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
RAB9A P51151 7/20 0.53
NPC1 O15118 6/20 0.53
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
BCL2L1 Q07817 1/20 0.52
BAD Q92934 1/20 0.52
ATM Q13315 1/20 0.52
PTPN1 P18031 1/20 0.50
PKM P14618 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 1/20 0.48
LTA4H P09960 1/20 0.48
CASP3 P42574 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286650 0.91 CES2 (0.48) CES2CES1CA1CA2RAB9A
SCHEMBL29112554 0.88 CES2 (0.46) CES2CES1CA1CA2RAB9A
SCHEMBL28597958 0.88 CES2 (0.46) CES2CES1CA1CA2RAB9A
SCHEMBL11880655 0.88 CES2 (0.46) CES2CES1CA1CA2RAB9A
SCHEMBL775620 0.86 CES2 (0.59) CES2CES1CA1CA2RAB9A
SCHEMBL11127178 0.86 CES2 (0.59) CES2CES1CA1CA2RAB9A
Ethylene SCHEMBL1366416 0.86 CES2 (0.43) CES2CES1CA1CA2RAB9A
Cyclopropane SCHEMBL18860160 0.83 KDM4E (0.42) CES2CES1CA1CA2RAB9A
SCHEMBL3876168 0.83 BCL2L1 (0.52) CES2CES1CA1CA2MAPT
SCHEMBL556622 0.82 CES2 (0.54) CES2CES1CA1CA2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041882-A1 METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS XENOPORT, INC. (US) 2010-02-18 US claimed
US-7662987-B2 Oxidation of 1-acyl alkyl compound under anhydrous condition XENOPORT, INC. (US) 2010-02-16 US claimed
US-20050070715-A1 Methods for synthesis of acyloxyalkyl compounds ARBOR PHARMACEUTICALS, LLC 2005-03-31 US claimed
US-4917815-A STABILIZED WITH THE CORRESPONDING CARBOXYLIC ACID, PERGLUTARIC ACID AND HYDROGEN PEROXIDE STERLING DRUG INC. (US) 1990-04-17 US claimed
US-4221660-A AROMATIC PERCARBOXYLIC ACID, FOR WATER SYSTEMS STERLING DRUG INC. (US) 1980-09-09 US claimed
EP-4634196-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES Momentive Performance Materials GmbH (DE) 2025-10-22 EP disclosed
WO-2024126692-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2024-06-20 WO disclosed
EP-2588502-B1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION NOURYON CHEMICALS INT BV (NL) 2021-03-31 EP disclosed
US-9353057-B2 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT, INC. (US) 2016-05-31 US disclosed
EP-2250143-B1 METHOD FOR THE ENZYMATIC KINETIC RESOLUTION OF ACYLOXYALKYL THIOCARBONATES USED FOR THE SYNTHESIS OF ACYLOXYALKYL CARBAMATES XENOPORT INC (US) 2016-04-20 EP disclosed
EP-2606175-B1 METHOD FOR REMOVING HEXENURONIC ACIDS ÅBO AKADEMI UNIVERSITY (FI) 2016-04-20 EP disclosed
US-8987391-B2 Polymerization process with in-situ initiator formation AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-03-24 US disclosed
US-20050222431-A1 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT, INC. 2005-10-06 US disclosed
US-4671891-A HALOGENATED PEROXYBENZOIC ACID AND BLEACH ACTIVATOR, SUCH AS 4-SULFOPHENYLACETATE, SODIUM SALT THE PROCTER & GAMBLE COMPANY (US) 1987-06-09 US disclosed
EP-0105690-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1984-04-18 EP disclosed
US-4259383-A PEROXY COMPOUNDS STERLING DRUG INC. (US) 1981-03-31 US disclosed
US-4221660-A AROMATIC PERCARBOXYLIC ACID, FOR WATER SYSTEMS STERLING DRUG INC. (US) 1980-09-09 US disclosed
US-4008175-A Organic acid anhydride-peroxydicarbonate composition PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3985720-A Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 PPG INDUSTRIES, INC. (US) 1976-10-12 US disclosed
US-3978032-A ALKALINE BUFFER, ANHYDRIDE, PERACID, ALKYL HALOFORMATE PPG INDUSTRIES, INC. (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070715-A1 Methods for synthesis of acyloxyalkyl compounds AADAC, CYP2D6, CYP3A7 CES2 14/4885CES1 56/4885CA1 854/4885
US-20050222431-A1 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof CPS1, ACMSD, NAAA CES2 17/4885CES1 33/4885CA1 23/4885
US-20100041882-A1 METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS AADAC, CYP2D6, CYP3A7 CES2 14/4885CES1 56/4885CA1 854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.