Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 10/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912285 | 0.94 | CSF1R (0.58) | CSF1RMAPTGAATHRBLMNA | |
| SCHEMBL2907950 | 0.93 | CSF1R (0.65) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2906337 | 0.93 | CSF1R (0.66) | CSF1RMAPTGAATHRBSMN1; SMN2 | |
| SCHEMBL2912047 | 0.90 | CSF1R (0.64) | CSF1RMAPTGAATHRBTP53 | |
| SCHEMBL2913622 | 0.89 | CSF1R (0.66) | CSF1RMAPTGAATHRBLMNA | |
| SCHEMBL2910481 | 0.89 | CSF1R (0.65) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2908736 | 0.89 | CSF1R (0.66) | CSF1RMAPTGAATHRBSMN1; SMN2 | |
| SCHEMBL2911338 | 0.88 | MAPT (0.56) | CSF1RMAPTGAATHRBLMNA | |
| SCHEMBL2911907 | 0.87 | CSF1R (0.66) | CSF1RMAPTGAATHRBSMN1; SMN2 | |
| SCHEMBL2912817 | 0.86 | CSF1R (0.58) | CSF1RMAPTGAATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |