Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 14/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910481 | 0.96 | CSF1R (0.65) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2912817 | 0.94 | CSF1R (0.58) | CSF1RMAPTGAATHRBKCNH2 | |
| SCHEMBL2911260 | 0.93 | CSF1R (0.65) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2911907 | 0.93 | CSF1R (0.66) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2912936 | 0.92 | CSF1R (0.56) | CSF1RMAPTGAATHRBKCNH2 | |
| SCHEMBL2913622 | 0.91 | CSF1R (0.66) | CSF1RMAPTGAATHRBNUDT1 | |
| SCHEMBL2912047 | 0.90 | CSF1R (0.64) | CSF1RMAPTGAATHRB | |
| SCHEMBL2912356 | 0.90 | CSF1R (0.58) | CSF1RMAPTGAATHRBKCNH2 | |
| SCHEMBL2911338 | 0.90 | MAPT (0.56) | CSF1RMAPTGAATHRB | |
| SCHEMBL2906337 | 0.87 | CSF1R (0.66) | CSF1RMAPTGAATHRBNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |
| US-20090270450-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | CSF1R, CSF3R, FLT3 | CSF1R 1/4885MAPT 3172/4885GAA 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.