Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903702 | 0.88 | HTT (0.51) | RAB9ARECQLKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13064249 | 0.84 | TSHR (0.50) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL1044642 | 0.83 | MAPT (0.45) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL27708492 | 0.82 | RAB9A (0.41) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL13210721 | 0.81 | NTRK1 (0.43) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL7786621 | 0.80 | RAB9A (0.40) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL13980917 | 0.80 | CNR1 (0.43) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL3074720 | 0.80 | TSHR (0.49) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL29437136 | 0.80 | MAPT (0.41) | RAB9ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL13210713 | 0.80 | MAPT (0.41) | RAB9ARECQLKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474407-B1 | DIFLUOROMETHYL THIAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | MRPL21, FOXM1, FLT3 | RAB9A 1338/4885RECQL 216/4885KMT2A 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.