Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210721 | 0.92 | NTRK1 (0.43) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL1044642 | 0.92 | MAPT (0.45) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL343339 | 0.91 | TDP1 (0.47) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL167980 | 0.91 | MAPT (0.41) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL29437136 | 0.91 | MAPT (0.41) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL13210713 | 0.91 | MAPT (0.41) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL13210812 | 0.89 | MAPT (0.40) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL29419103 | 0.89 | ABCG2 (0.47) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL121792 | 0.89 | ABCG2 (0.47) | TSHRHTTMAPTHSD17B10USP2 | |
| SCHEMBL20514734 | 0.89 | ALDH1A1 (0.41) | TSHRHTTMAPTHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910126-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2255658-A1 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2253210-A1 | Agent combinations | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |