Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962961 | 0.76 | NPC1 (0.48) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL25274620 | 0.74 | CYP2A6 (0.43) | ALDH1A1HPGDHSD17B10BCL2L1KMT2A | |
| SCHEMBL20406101 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10KMT2ACCNB2 | |
| SCHEMBL8957712 | 0.72 | — | — | |
| SCHEMBL30442890 | 0.71 | ALDH1A1 (0.67) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL29623192 | 0.71 | ALDH1A1 (0.67) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL28574 | 0.71 | ALDH1A1 (0.67) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL27659427 | 0.71 | ALDH1A1 (0.67) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL13907548 | 0.71 | KMT2A (0.46) | IDO1ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL1456413 | 0.69 | KDM4E (0.48) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143028-B | Hydroxyphenyl pyridazine Mannich base compound, and preparation method and application thereof | 四川大学 | 2024-12-20 | — | — | CN | claimed |
| CN-117143027-B | 3-Benzyloxy-6-hydroxyphenylpyridazine compound as well as preparation method and application thereof | 四川大学 | 2024-12-20 | — | — | CN | claimed |
| CN-117143027-A | 3-benzyloxy-6-hydroxyphenylpyridazine compound as well as preparation method and application thereof | 四川大学 | 2023-12-01 | — | — | CN | claimed |
| CN-117143028-A | Hydroxyphenyl pyridazine Mannich base compound, and preparation method and application thereof | 四川大学 | 2023-12-01 | — | — | CN | claimed |
| CN-117143028-B | Hydroxyphenyl pyridazine Mannich base compound, and preparation method and application thereof | 四川大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-117143027-B | 3-Benzyloxy-6-hydroxyphenylpyridazine compound as well as preparation method and application thereof | 四川大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-117143028-A | Hydroxyphenyl pyridazine Mannich base compound, and preparation method and application thereof | 四川大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-117143027-A | 3-benzyloxy-6-hydroxyphenylpyridazine compound as well as preparation method and application thereof | 四川大学 | 2023-12-01 | — | — | CN | disclosed |