Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959244 | 0.81 | CYP19A1 (0.49) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL31214474 | 0.80 | — | — | |
| SCHEMBL188902 | 0.80 | — | — | |
| SCHEMBL5685526 | 0.80 | NPC1 (0.49) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL29594708 | 0.78 | RIPK1 (0.47) | NPC1RIPK1PDE5ARAB9AMAPT | |
| SCHEMBL20821415 | 0.78 | DPP4 (0.50) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL28545758 | 0.78 | RIPK1 (0.47) | NPC1RIPK1PDE5ARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL4955115 | 0.78 | — | — | |
| Methane SCHEMBL28008411 | 0.78 | — | — | |
| SCHEMBL29693684 | 0.77 | PTPRC (0.50) | KMT2AMEN1RIPK1PDE5AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771027-A | Lysophosphatidic acid receptor antagonists and process for their preparation | 武汉朗来科技发展有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-110092798-A | It is a kind of as the heterocyclic compound and its synthetic method of FGFR inhibitor and application | 上海新契博生物科技有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-110093793-A | Inkjet pigments printing and dyeing treatment fluid composition, pigment printing and dyeing inkjet ink composition group and inkjet pigments dyeing method | 精工爱普生株式会社 | 2019-08-06 | — | — | CN | disclosed |
| CN-107406566-A | Polyisocyantates composition, polyurethane resin and coating | 三井化学株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-107001558-A | Self-repairing urethane resin raw material, self-repairing urethane resin, self-repairing coating material, self-repairing elastomer material, method for producing self-repairing urethane resin raw material, and method for producing self-repairing urethane resin | 三井化学株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-107001557-A | Self-repairing urethane resin raw material, self-repairing urethane resin, self-repairing coating material, self-repairing elastomer material, method for producing self-repairing urethane resin raw material, and method for producing self-repairing urethane resin | 三井化学株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-103347852-B | Pentanediisocyanate, process for producing pentamethylenediisocyanate, polyisocyanate composition, polyurethane resin, and polyurea resin | MITSUI CHEMICALS, INC. (JP) | 2016-04-13 | — | — | CN | disclosed |
| US-20090076268-A1 | Facile assembly of fused benzofuro-heterocycles | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-19 | — | — | US | disclosed |
| US-20090076268-A1 | Facile assembly of fused benzofuro-heterocycles | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-19 | — | — | US | disclosed |
| US-20090076268-A1 | Facile assembly of fused benzofuro-heterocycles | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-19 | — | — | US | disclosed |
| WO-2009035668-A1 | FACILE ASSEMBLY OF FUSED BENZOFURO-HETEROCYCLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035668-A1 | FACILE ASSEMBLY OF FUSED BENZOFURO-HETEROCYCLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076268-A1 | Facile assembly of fused benzofuro-heterocycles | BICRA, DDC, DDT | NPC1 4166/4885KMT2A 1540/4885MEN1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.