Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489711 | 0.84 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30318694 | 0.84 | APLNR (0.46) | APLNRGRIN2BGRIN1KDM4ECYP1A2 | |
| SCHEMBL31392878 | 0.84 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL22585597 | 0.84 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30218199 | 0.84 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30085317 | 0.82 | APLNR (0.49) | APLNRGRIN2BGRIN1KDM4E | |
| SCHEMBL20470389 | 0.82 | APLNR (0.49) | APLNRGRIN2BGRIN1KDM4E | |
| SCHEMBL20832717 | 0.82 | APLNR (0.45) | APLNRGRIN2BGRIN1KDM4ECYP1A2 | |
| SCHEMBL3702647 | 0.82 | APLNR (0.45) | APLNRGRIN2BGRIN1KDM4ECYP1A2 | |
| SCHEMBL18224526 | 0.79 | APLNR (0.46) | APLNRGRIN2BGRIN1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120439-A | FGFR3 inhibitor compounds | 伊莱利利公司 | 2023-11-24 | — | — | CN | disclosed |