Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489711 | 1.00 | APLNR (0.50) | APLNRESR1ESR2LMNACYP11B1 | |
| SCHEMBL31392878 | 1.00 | APLNR (0.50) | APLNRESR1ESR2LMNACYP11B1 | |
| SCHEMBL22585597 | 1.00 | APLNR (0.50) | APLNRESR1ESR2LMNACYP11B1 | |
| SCHEMBL18224526 | 0.87 | APLNR (0.46) | APLNRCYP11B1CYP11B2GRIN2BGRIN1 | |
| SCHEMBL29115176 | 0.84 | APLNR (0.46) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30318694 | 0.84 | APLNR (0.46) | APLNRGRIN2BGRIN1 | |
| SCHEMBL3942632 | 0.83 | APLNR (0.43) | APLNRGRIN2BGRIN1 | |
| SCHEMBL20832717 | 0.82 | APLNR (0.45) | APLNRGRIN2BGRIN1 | |
| SCHEMBL3702647 | 0.82 | APLNR (0.45) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30085317 | 0.82 | APLNR (0.49) | APLNRLMNAGRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079985-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079984-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079983-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-115867280-B | 5-Amino-8- (4-pyridyl) - [1,2,4] triazolo [4,3-C ] pyrimidin-3-one compounds for anticancer use | 奈克斯拉制药英国有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-115867280-A | 5-amino-8- (4-pyridinyl) - [1,2,4] triazolo [4,3-C ] pyrimidin-3-one compounds for use in cancer therapy | 赫普泰雅治疗有限公司 | 2023-03-28 | — | — | CN | disclosed |