SCHEMBL29115452

SCHEMBL29115452

N#CSc1c(Cl)cccc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 5/20 0.39
AR P10275 5/20 0.39
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
GLA P06280 2/20 0.35
GAA P10253 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
P2RX7 Q99572 1/20 0.34
LDHA P00338 1/20 0.34
LDHB P07195 1/20 0.34
TYK2 P29597 1/20 0.33
HSD11B1 P28845 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CUL4A Q13619 1/20 0.33
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14290259 0.80 CYP1A2 (0.38) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL28995326 0.80 AR (0.38) SLC22A12ARHSD11B1CUL4APTGS2
SCHEMBL28918930 0.79 P2RX7 (0.39) SLC22A12ARKDM4EALDH1A1GLA
SCHEMBL29115306 0.79 AR (0.34) ARP2RX7HSD11B1L3MBTL1CUL4A
SCHEMBL21192823 0.76 P2RX7 (0.41) SLC22A12ARP2RX7LDHALDHB
SCHEMBL10976334 0.76 P2RX7 (0.37) SLC22A12ARKDM4EP2RX7LDHA
SCHEMBL29115282 0.72 GLA (0.35) ARALDH1A1GLAGAA
SCHEMBL10354613 0.72 TSHR (0.43) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL1275083 0.72 SLC22A12 (0.55) SLC22A12ARKDM4EALDH1A1GLA
SCHEMBL33745024 0.71 P2RX7 (0.38) ALDH1A1P2RX7TYK2HSD11B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703728-A Trifluoromethyl phenyl thiocyanate compound 上海泰初化工技术有限公司 2023-02-17 CN disclosed