Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 11/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964187 | 0.88 | RIPK1 (0.51) | RIPK1KDM1AESR1ESR2MEN1 | |
| SCHEMBL29891706 | 0.81 | RIPK1 (0.54) | RIPK1KDM1AESR1ESR2CHRM3 | |
| SCHEMBL27077252 | 0.76 | RIPK1 (0.51) | RIPK1KDM1AESR1ESR2EPHX2 | |
| SCHEMBL27077325 | 0.75 | KDM1A (0.56) | RIPK1KDM1AESR1ESR2 | |
| SCHEMBL1576663 | 0.74 | RIPK1 (0.73) | RIPK1ESR1ESR2EPHX2 | |
| SCHEMBL28171621 | 0.73 | RIPK1 (0.67) | RIPK1ESR1ESR2EPHX2BACE1 | |
| SCHEMBL29893426 | 0.72 | RIPK1 (0.53) | RIPK1KDM1AESR1ESR2EPHX2 | |
| SCHEMBL29116126 | 0.72 | KDM1A (0.52) | RIPK1KDM1AKMT2AEPHX2 | |
| SCHEMBL29891684 | 0.72 | KDM1A (0.52) | RIPK1KDM1AKMT2AEPHX2 | |
| SCHEMBL29892002 | 0.72 | KDM1A (0.52) | RIPK1KDM1AKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |