Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2911455 | 0.87 | HRH3 (0.41) | METHRH3CSF1RGSK3BGSK3A | |
| Ammonia Solution, Strong SCHEMBL2912310 | 0.86 | HRH3 (0.41) | METHRH3CSF1RGSK3BGSK3A | |
| Ammonia Solution, Strong SCHEMBL2908714 | 0.82 | SMN1; SMN2 (0.42) | GSK3BGSK3ADPP4DPP8DPP9 | |
| SCHEMBL2912205 | 0.72 | GSK3B (0.49) | GSK3BGSK3ADPP4DPP8 | |
| SCHEMBL2907104 | 0.72 | GSK3B (0.49) | GSK3BGSK3ADPP4DPP8 | |
| SCHEMBL2914191 | 0.72 | GSK3B (0.47) | GSK3BGSK3A | |
| Ammonia Solution, Strong SCHEMBL2909794 | 0.69 | GSK3B (0.41) | GSK3BGSK3ADPP4 | |
| Ammonia Solution, Strong SCHEMBL2906802 | 0.69 | GSK3B (0.41) | GSK3BGSK3ADPP4 | |
| SCHEMBL2903944 | 0.69 | GSK3B (0.51) | GSK3BGSK3A | |
| Ammonia Solution, Strong SCHEMBL2912932 | 0.68 | SMN1; SMN2 (0.47) | GSK3BGSK3ADPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |