Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366323 | 1.00 | HDAC1 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL25333055 | 0.93 | ALDH1A1 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL2803168 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL18049455 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL905673 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL9169265 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL3523840 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL14627814 | 0.90 | HDAC3 (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11672538 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B | |
| SCHEMBL7593121 | 0.90 | LTA4H (0.46) | ALDH1A1TSHRSLC6A2MAPK1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222815-A1 | PHOTOALIGNMENT COMPOSITION | Rolic Ltd. (CH) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080271-A1 | PHOTOALIGNMENT COMPOSITION | ROLIC LTD. (CH) | 2009-07-02 | — | — | WO | disclosed |