Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117236 | 1.00 | CTSL (0.49) | CTSLCTSBCTSKCHRNB2CHRNB4 | |
| SCHEMBL18426023 | 0.91 | GRIN2D (0.52) | CTSLCTSBCTSKGRIN2DGRIN3B | |
| SCHEMBL2526379 | 0.91 | GRIN2D (0.52) | CTSLCTSBCTSKGRIN2DGRIN3B | |
| SCHEMBL2525766 | 0.91 | GRIN2D (0.52) | CTSLCTSBCTSKGRIN2DGRIN3B | |
| SCHEMBL11175416 | 0.89 | MAPK1 (0.48) | CTSLCTSBCTSKCHRNB2CHRNB4 | |
| SCHEMBL22581151 | 0.89 | GRIN2D (0.56) | CTSLCTSBCTSKCHRNB2CHRNB4 | |
| SCHEMBL8482073 | 0.89 | GRIN2D (0.56) | CTSLCTSBCTSKCHRNB2CHRNB4 | |
| SCHEMBL2940477 | 0.85 | CTSL (0.57) | CTSLCTSBCTSKGRIN2DGRIN3B | |
| SCHEMBL18669297 | 0.84 | LMNA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN2D | |
| SCHEMBL18669294 | 0.84 | LMNA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177744-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2023-12-05 | — | — | CN | disclosed |