Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21490455 | 0.83 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28283970 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL28820059 | 0.82 | ALDH1A1 (0.56) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL24177783 | 0.81 | KMT2A (0.58) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL21590285 | 0.81 | GAA (0.57) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12551243 | 0.79 | FAAH (0.45) | LMNAALDH1A1SMN1; SMN2CYP19A1KMT2A | |
| Hydrochloric Acid SCHEMBL27859860 | 0.79 | EGFR (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| Bromide SCHEMBL15967768 | 0.78 | EGFR (0.45) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL24849249 | 0.77 | KMT2A (0.52) | LMNAALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL13150840 | 0.77 | MEN1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907288-B | Application of nitrobenzene compounds in preparation of pseudomonas aeruginosa quorum sensing inhibitor | 中国医学科学院医药生物技术研究所 | 2023-12-08 | — | — | CN | disclosed |