Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176021 | 0.92 | RARB (0.66) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL13176015 | 0.82 | RARB (0.48) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL2917393 | 0.81 | ALDH1A1 (0.47) | RARBALDH1A1RARAMAPTPLK1 | |
| SCHEMBL28255947 | 0.81 | HSD17B10 (0.62) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL2915987 | 0.80 | ALDH1A1 (0.49) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL9418034 | 0.78 | HSD17B10 (0.56) | RARBALDH1A1KMT2APLK1HSD17B10 | |
| SCHEMBL1811178 | 0.78 | RARB (0.73) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL1815479 | 0.77 | RARB (0.53) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL16487163 | 0.77 | RARB (0.66) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL2402922 | 0.77 | RARB (0.71) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1388538-A1 | Polymerisation Initiator | MERCK PATENT GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |