Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915987 | 0.89 | ALDH1A1 (0.49) | RARBHRH3MEN1ALDH1A1RARA | |
| SCHEMBL2911940 | 0.82 | RARB (0.56) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL13657327 | 0.77 | THRA (0.58) | RARBHRH3MEN1ALDH1A1RARA | |
| SCHEMBL28255947 | 0.74 | HSD17B10 (0.62) | RARBHRH3MEN1ALDH1A1RARA | |
| SCHEMBL13176021 | 0.73 | RARB (0.66) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL51732 | 0.72 | THRA (0.61) | RARBHRH3MEN1ALDH1A1RARA | |
| SCHEMBL2914565 | 0.72 | ALDH1A1 (0.56) | HRH3ALDH1A1MAPTMMP2MMP9 | |
| SCHEMBL14225072 | 0.72 | ALDH1A1 (0.44) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9418034 | 0.72 | HSD17B10 (0.56) | RARBALDH1A1KMT2APLK1THRA | |
| SCHEMBL1811178 | 0.72 | RARB (0.73) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |