Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119723 | 0.88 | ACHE (0.42) | MAPK7HDAC1HDAC2RPS6KA2TAS2R8 | |
| Hydrochloric Acid SCHEMBL28529636 | 0.84 | TAS2R8 (0.41) | MAPK7RPS6KA2TAS2R8HRH4KDM1A | |
| SCHEMBL12093358 | 0.80 | HDAC1 (0.43) | MAPK7HDAC1HDAC2RPS6KA2HRH3 | |
| Hydrochloric Acid SCHEMBL28530896 | 0.78 | JAK2 (0.41) | MAPK7HDAC1HDAC2TAS2R8KDM1A | |
| SCHEMBL29741306 | 0.78 | HDAC1 (0.42) | MAPK7HDAC1HDAC2RPS6KA2HRH3 | |
| SCHEMBL1703769 | 0.78 | HDAC1 (0.47) | MAPK7HDAC1HDAC2RPS6KA2HRH3 | |
| SCHEMBL1582109 | 0.78 | HDAC1 (0.42) | MAPK7HDAC1HDAC2RPS6KA2HRH3 | |
| SCHEMBL12089573 | 0.77 | HDAC1 (0.42) | MAPK7HDAC1HDAC2RPS6KA2HRH3 | |
| Hydrochloric Acid SCHEMBL28522391 | 0.76 | TAS2R8 (0.42) | TAS2R8HRH4KDM1AFGFR1FGFR2 | |
| SCHEMBL24493320 | 0.76 | HDAC1 (0.43) | MAPK7HDAC1HDAC2RPS6KA2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745278-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-12 | — | — | CN | disclosed |