Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119670 | 0.89 | CDK9 (0.45) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL24493185 | 0.79 | CCNT1 (0.43) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL30578237 | 0.79 | CCNT1 (0.43) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL13103482 | 0.78 | CCNT1 (0.45) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL29650126 | 0.77 | ITGB3 (0.40) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL29650108 | 0.75 | CCNT1 (0.40) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL27096029 | 0.75 | CCNT1 (0.40) | CDK9USP1WDR48CCNT1PIM1 | |
| SCHEMBL27096001 | 0.74 | CCNT1 (0.42) | CDK9CCNT1PIM1KCNH2PIM2 | |
| SCHEMBL13118523 | 0.72 | GRIN2B (0.57) | CDK9USP1WDR48CCNT1USP30 | |
| SCHEMBL27096005 | 0.71 | PIM1 (0.43) | USP1WDR48CCNT1PIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745278-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-12 | — | — | CN | disclosed |