Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119969 | 0.89 | L3MBTL3 (0.61) | EPHX2MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL425630 | 0.85 | PKM (0.54) | HPGDPHGDHEPHX2KMT2APKM | |
| SCHEMBL29119937 | 0.84 | PHGDH (0.58) | ERN1HPGDPHGDHJAK2MEN1 | |
| SCHEMBL29119932 | 0.84 | ERN1 (0.54) | ERN1HPGDPHGDHJAK2EPHX2 | |
| SCHEMBL5318815 | 0.82 | PHGDH (0.61) | ERN1HPGDPHGDHJAK2KMT2A | |
| SCHEMBL29119933 | 0.81 | KMT2A (0.57) | ERN1HPGDPHGDHJAK2MEN1 | |
| SCHEMBL29119963 | 0.81 | HPGD (0.49) | ERN1HPGDPHGDHJAK2MEN1 | |
| SCHEMBL8167348 | 0.81 | ERN1 (0.69) | ERN1HPGDPHGDHJAK2EPHX2 | |
| SCHEMBL8172365 | 0.80 | EPHX2 (0.71) | ERN1HPGDPHGDHEPHX2MEN1 | |
| SCHEMBL13952065 | 0.78 | HPGD (0.65) | ERN1HPGDPHGDHJAK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203211-A | Imidazo thiazole derivative, preparation method and application thereof | 中国海洋大学 | 2023-12-08 | — | — | CN | disclosed |