Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308675 | 0.80 | FOLH1 (0.53) | FOLH1POLBSCN9A | |
| SCHEMBL3222189 | 0.76 | POLB (0.37) | FOLH1POLBSCN9A | |
| SCHEMBL28262175 | 0.76 | FOLH1 (0.36) | FOLH1POLBSCN9A | |
| SCHEMBL27858273 | 0.76 | FOLH1 (0.36) | FOLH1POLBSCN9A | |
| SCHEMBL3222193 | 0.76 | POLB (0.37) | FOLH1POLBSCN9A | |
| SCHEMBL24939389 | 0.75 | CA1 (0.35) | FOLH1TSHRPOLBGBA1 | |
| SCHEMBL29120919 | 0.75 | TSHR (0.37) | FOLH1TSHR | |
| SCHEMBL29120909 | 0.75 | TSHR (0.37) | FOLH1TSHR | |
| SCHEMBL29120908 | 0.75 | TSHR (0.37) | FOLH1TSHR | |
| SCHEMBL27753796 | 0.71 | SLC7A5 (0.36) | FOLH1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641863-B | Intermediate for synthesizing carfilzomib and synthesis of pharmaceutically acceptable salt thereof | 美国安进公司 | 2023-10-20 | — | — | CN | disclosed |