Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.53 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222189 | 0.81 | POLB (0.37) | FOLH1LAP3POLBSCN9A | |
| SCHEMBL3222193 | 0.81 | POLB (0.37) | FOLH1LAP3POLBSCN9A | |
| SCHEMBL28262175 | 0.81 | FOLH1 (0.36) | FOLH1LAP3POLBALDH1A1SCN9A | |
| SCHEMBL27858273 | 0.81 | FOLH1 (0.36) | FOLH1LAP3POLBSCN9A | |
| SCHEMBL29120907 | 0.80 | FOLH1 (0.35) | FOLH1POLBSCN9A | |
| SCHEMBL24939389 | 0.76 | CA1 (0.35) | FOLH1POLBALDH1A1CTSLCTSB | |
| SCHEMBL27753796 | 0.76 | SLC7A5 (0.36) | FOLH1LAP3POLBRNPEPSLC7A5 | |
| SCHEMBL28773695 | 0.75 | CTSK (0.38) | POLBCTSLCTSBCTSSCTSK | |
| SCHEMBL27726431 | 0.75 | CTSK (0.38) | LAP3POLBRNPEPSLC7A5CTSL | |
| SCHEMBL27910718 | 0.75 | CTSK (0.38) | LAP3POLBRNPEPSLC7A5CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |