Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828704 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29121241 | 0.92 | GSTA1 (0.34) | — | |
| SCHEMBL28828586 | 0.92 | GSTA1 (0.34) | — | |
| SCHEMBL29121172 | 0.90 | KDM4E (0.32) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29121312 | 0.89 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL28828685 | 0.88 | KDM4E (0.32) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL28828606 | 0.88 | CNR1 (0.36) | — | |
| SCHEMBL29121247 | 0.86 | PARP10 (0.39) | KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL28828590 | 0.86 | PARP10 (0.39) | KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL28828509 | 0.85 | MCL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | claimed |
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | disclosed |