Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121268 | 0.90 | FFAR1 (0.36) | CYP3A4LMNAFFAR1PTGS2AKR1C3 | |
| SCHEMBL29121237 | 0.90 | APP (0.37) | APPSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL28828612 | 0.90 | APP (0.37) | APPSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL27200883 | 0.88 | FFAR4 (0.41) | — | |
| SCHEMBL29121175 | 0.88 | FFAR4 (0.41) | — | |
| SCHEMBL29121324 | 0.87 | FFAR4 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29228166 | 0.87 | FFAR4 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29121236 | 0.87 | PRKAB2 (0.38) | APPCYP3A4CYP2C19CYP2C9FFAR1 | |
| SCHEMBL29121310 | 0.86 | FFAR4 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29121223 | 0.86 | SLC6A2 (0.33) | APPSLC6A2SLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | claimed |
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | disclosed |