Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828612 | 1.00 | APP (0.37) | APPSLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL29121306 | 0.90 | APP (0.35) | APPSLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL28828502 | 0.90 | RXRA (0.34) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL29121190 | 0.90 | RXRA (0.34) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL29121192 | 0.88 | FFAR4 (0.42) | FFAR4 | |
| SCHEMBL28828458 | 0.88 | FFAR4 (0.42) | FFAR4 | |
| SCHEMBL28828600 | 0.87 | EPHX1 (0.36) | SLC6A2SLC6A4SLC6A3FFAR4 | |
| SCHEMBL28828393 | 0.86 | AKR1C3 (0.37) | HSP90AA1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL29121219 | 0.86 | PRKAB2 (0.39) | APPSLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL28828510 | 0.86 | PRKAB2 (0.39) | APPSLC6A2SLC6A4SLC6A3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | claimed |
| CN-117222645-A | Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same | 柳韩洋行 | 2023-12-12 | — | — | CN | disclosed |