Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122009 | 0.84 | USP30 (0.41) | USP30KRASIDO1TDO2NAMPT | |
| SCHEMBL29122435 | 0.84 | USP30 (0.42) | USP30KRASIDO1TDO2NR1H2 | |
| SCHEMBL30676500 | 0.82 | ROCK1 (0.42) | USP30KRASIDO1TDO2NR1H2 | |
| SCHEMBL29122054 | 0.82 | ROCK1 (0.42) | USP30KRASIDO1TDO2NR1H2 | |
| SCHEMBL29121906 | 0.78 | USP30 (0.42) | USP30IDO1TDO2FPR2 | |
| SCHEMBL29121909 | 0.78 | USP30 (0.42) | USP30IDO1TDO2FPR2 | |
| SCHEMBL29122015 | 0.78 | GPR119 (0.43) | USP30BACE1FPR2 | |
| SCHEMBL30676565 | 0.77 | ELANE (0.46) | USP30KRASIDO1TDO2NAMPT | |
| SCHEMBL29121890 | 0.77 | ELANE (0.46) | USP30KRASIDO1TDO2NAMPT | |
| SCHEMBL29340428 | 0.76 | MAPK8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |