Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 5/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121838 | 0.84 | USP30 (0.41) | USP30IDO1TDO2NAMPTROCK1 | |
| SCHEMBL29121922 | 0.83 | USP30 (0.43) | USP30KRASEPHA2FPR2L3MBTL1 | |
| SCHEMBL30676565 | 0.83 | ELANE (0.46) | USP30IDO1TDO2NAMPTROCK1 | |
| SCHEMBL29121890 | 0.83 | ELANE (0.46) | USP30IDO1TDO2NAMPTROCK1 | |
| SCHEMBL29121912 | 0.81 | MAPK8 (0.50) | MAPK8L3MBTL1 | |
| SCHEMBL29122054 | 0.78 | ROCK1 (0.42) | USP30IDO1TDO2NAMPTROCK1 | |
| SCHEMBL30676500 | 0.78 | ROCK1 (0.42) | USP30IDO1TDO2NAMPTROCK1 | |
| SCHEMBL29122384 | 0.78 | USP30 (0.44) | USP30IDO1TDO2EPHA2FPR2 | |
| SCHEMBL29122496 | 0.78 | FPR2 (0.44) | USP30FPR2 | |
| SCHEMBL31430434 | 0.76 | EGFR (0.41) | MAPK8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |