Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134131 | 0.89 | TLR7 (0.76) | TLR7NUDT1 | |
| SCHEMBL3133950 | 0.85 | TLR7 (0.77) | TLR7NUDT1 | |
| SCHEMBL3146807 | 0.84 | TLR7 (0.75) | TLR7NUDT1 | |
| SCHEMBL3141800 | 0.83 | TLR7 (0.80) | TLR7NUDT1 | |
| SCHEMBL3139086 | 0.82 | TLR7 (1.00) | TLR7NUDT1 | |
| SCHEMBL3137353 | 0.81 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL3137361 | 0.81 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL16206181 | 0.80 | TLR7 (1.00) | TLR7NUDT1 | |
| Urethane SCHEMBL3128318 | 0.80 | TLR7 (0.64) | TLR7NUDT1 | |
| SCHEMBL18221128 | 0.79 | TLR7 (1.00) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372836-B2 | Spray dried formulation | BEND RESEARCH, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372836-B2 | Spray dried formulation | BEND RESEARCH, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372836-B2 | Spray dried formulation | BEND RESEARCH, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| EP-2101741-B1 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | BEND RES INC (US) | 2010-08-11 | — | — | EP | disclosed |
| EP-2101741-B1 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | BEND RES INC (US) | 2010-08-11 | — | — | EP | disclosed |
| US-20100029667-A1 | Spray dried formulation | BEND RESEARCH INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029667-A1 | Spray dried formulation | BEND RESEARCH INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029667-A1 | Spray dried formulation | BEND RESEARCH INC. | 2010-02-04 | — | — | US | disclosed |
| US-7642350-B2 | Purine derivatives | PFIZER LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-7642350-B2 | Purine derivatives | PFIZER LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-7642350-B2 | Purine derivatives | PFIZER LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| EP-2101741-A2 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | BEND RESEARCH, INC. (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008047201-A2 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008047201-A2 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |
| US-20060264448-A1 | Purine derivatives | PFIZER LIMITED | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029667-A1 | Spray dried formulation | PRKG1, PDE7A, PDE10A | TLR7 2925/4885NUDT1 2522/4885 |
| US-20060264448-A1 | Purine derivatives | TLR9, TLR7, TLR1 | TLR7 2/4885NUDT1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.