Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.65 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137353 | 0.95 | TLR7 (0.65) | TLR7NUDT1IL6 | |
| Urethane SCHEMBL3128318 | 0.94 | TLR7 (0.64) | TLR7NUDT1IL6 | |
| SCHEMBL2908582 | 0.92 | TLR7 (0.71) | TLR7NUDT1 | |
| SCHEMBL3141800 | 0.82 | TLR7 (0.80) | TLR7NUDT1 | |
| SCHEMBL2912228 | 0.81 | TLR7 (0.70) | TLR7NUDT1 | |
| SCHEMBL14944576 | 0.79 | TLR7 (0.68) | TLR7NUDT1 | |
| SCHEMBL18221128 | 0.79 | TLR7 (1.00) | TLR7NUDT1IL6 | |
| SCHEMBL3139086 | 0.79 | TLR7 (1.00) | TLR7NUDT1 | |
| SCHEMBL13522623 | 0.78 | TLR7 (0.43) | TLR7 | |
| SCHEMBL3134131 | 0.77 | TLR7 (0.76) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642350-B2 | Purine derivatives | PFIZER LIMITED (GB) | 2010-01-05 | — | — | US | claimed |
| US-20060264448-A1 | Purine derivatives | PFIZER LIMITED | 2006-11-23 | — | — | US | claimed |
| US-7642350-B2 | Purine derivatives | PFIZER LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20060264448-A1 | Purine derivatives | PFIZER LIMITED | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264448-A1 | Purine derivatives | TLR9, TLR7, TLR1 | TLR7 2/4885NUDT1 42/4885IL6 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.