Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729001 | 0.88 | GSK3B (0.43) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL31222852 | 0.86 | L3MBTL1 (0.46) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL1437636 | 0.79 | GSK3B (0.44) | HSD17B10TSHRGSK3BNPSR1PKM | |
| SCHEMBL319034 | 0.79 | GSK3B (0.53) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL12271839 | 0.79 | L3MBTL1 (0.42) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL613592 | 0.78 | KDM4E (0.40) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL4337879 | 0.78 | KMT2A (0.54) | HSD17B10ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL1971697 | 0.78 | MAPT (0.44) | HSD17B10ALDH1A1HPGDKDM4EATM | |
| SCHEMBL1374020 | 0.78 | TSHR (0.44) | HSD17B10HPGDL3MBTL1KDM4ETSHR | |
| SCHEMBL2730725 | 0.78 | MAPT (0.44) | HSD17B10ALDH1A1HPGDKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120450-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |