Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122566 | 0.86 | HSD17B10 (0.42) | L3MBTL1POLBMAPTHSD17B10TSHR | |
| SCHEMBL2729001 | 0.85 | GSK3B (0.43) | L3MBTL1POLBMAPTHSD17B10TSHR | |
| SCHEMBL31222900 | 0.85 | POLB (0.41) | L3MBTL1POLBMAPTKMT2AGSK3B | |
| SCHEMBL8570554 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBMAPTHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL8570552 | 0.79 | L3MBTL1 (0.51) | L3MBTL1POLBMAPTHSD17B10TSHR | |
| SCHEMBL319034 | 0.77 | GSK3B (0.53) | L3MBTL1MAPTHSD17B10TSHRKMT2A | |
| SCHEMBL1971697 | 0.75 | MAPT (0.44) | MAPTHSD17B10TSHRKMT2AGSK3B | |
| SCHEMBL2730725 | 0.75 | MAPT (0.44) | MAPTHSD17B10TSHRKMT2AGSK3B | |
| SCHEMBL1374020 | 0.75 | TSHR (0.44) | L3MBTL1POLBMAPTHSD17B10TSHR | |
| SCHEMBL612156 | 0.74 | MAPT (0.42) | L3MBTL1POLBMAPTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676476-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | Aquinnah Pharmaceuticals, Inc. (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024187126-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | AQUINNAH PHARMACEUTICALS, INC. (US) | 2024-09-12 | — | — | WO | disclosed |