Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122614 | 1.00 | POLB (0.35) | POLBPPARGATMRXFP1NCOR2 | |
| SCHEMBL29121909 | 0.85 | USP30 (0.42) | FPR2BTK | |
| SCHEMBL29121906 | 0.85 | USP30 (0.42) | FPR2BTK | |
| SCHEMBL29122015 | 0.80 | GPR119 (0.43) | CNR1FPR2CYP3A4 | |
| SCHEMBL29122350 | 0.80 | TEAD1 (0.37) | POLBCNR1FPR2BTKL3MBTL3 | |
| SCHEMBL29122348 | 0.80 | TEAD1 (0.37) | POLBCNR1FPR2BTKL3MBTL3 | |
| SCHEMBL29121967 | 0.80 | MAPT (0.36) | POLBPPARGATMRXFP1NCOR2 | |
| SCHEMBL29122457 | 0.80 | MAPT (0.38) | POLBPPARGATMRXFP1NCOR2 | |
| SCHEMBL29123043 | 0.78 | POLB (0.40) | POLBPPARGATMRXFP1NCOR2 | |
| SCHEMBL29122435 | 0.78 | USP30 (0.42) | FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |