Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268756 | 0.93 | FAP (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912291 | 0.90 | ABCB11 (0.42) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2914228 | 0.88 | ABCB11 (0.42) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2939529 | 0.88 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4415990 | 0.87 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| Maleic Acid SCHEMBL4395451 | 0.87 | FAP (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4419762 | 0.87 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2913633 | 0.85 | FAP (0.62) | ABCB11POLA1POLGFAPSLC22A6 | |
| Malic Acid SCHEMBL27872847 | 0.84 | ABCB11 (0.38) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4422979 | 0.83 | ABCB11 (0.36) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |