Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123584 | 1.00 | LTA4H (0.43) | LTA4HKCNH2FFAR1SCN9AMAPT | |
| SCHEMBL29123608 | 0.89 | LTA4H (0.52) | LTA4HKCNH2FFAR1SCN9AMAPT | |
| SCHEMBL29123605 | 0.89 | LTA4H (0.52) | LTA4HKCNH2FFAR1SCN9AMAPT | |
| SCHEMBL29123473 | 0.87 | SCN9A (0.46) | LTA4HFFAR1SCN9AFPR2MAPK1 | |
| SCHEMBL29123469 | 0.87 | SCN9A (0.46) | LTA4HFFAR1SCN9AFPR2MAPK1 | |
| SCHEMBL29123726 | 0.87 | LTA4H (0.42) | LTA4HKCNH2FFAR1SCN9AMAPT | |
| SCHEMBL29123730 | 0.87 | LTA4H (0.42) | LTA4HKCNH2FFAR1SCN9AMAPT | |
| SCHEMBL24665357 | 0.86 | LTA4H (0.58) | LTA4HKCNH2FFAR1MAPTSMN1; SMN2 | |
| SCHEMBL27204649 | 0.86 | LTA4H (0.58) | LTA4HKCNH2FFAR1MAPTSMN1; SMN2 | |
| SCHEMBL29123438 | 0.85 | LTA4H (0.63) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |