Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123469 | 1.00 | SCN9A (0.46) | SCN9AMAPK1FFAR1LTA4HGAA | |
| SCHEMBL29123397 | 0.90 | SCN9A (0.54) | SCN9AFFAR1LTA4HFPR2 | |
| SCHEMBL29123393 | 0.90 | SCN9A (0.54) | SCN9AFFAR1LTA4HFPR2 | |
| SCHEMBL29123534 | 0.88 | MAPK1 (0.44) | SCN9AMAPK1FFAR1GAA | |
| SCHEMBL29123584 | 0.87 | LTA4H (0.43) | SCN9AMAPK1FFAR1LTA4HFPR2 | |
| SCHEMBL29123582 | 0.87 | LTA4H (0.43) | SCN9AMAPK1FFAR1LTA4HFPR2 | |
| SCHEMBL29123726 | 0.87 | LTA4H (0.42) | SCN9AFFAR1LTA4H | |
| SCHEMBL29123730 | 0.87 | LTA4H (0.42) | SCN9AFFAR1LTA4H | |
| SCHEMBL24664170 | 0.86 | LTA4H (0.54) | SCN9AMAPK1FFAR1LTA4HGAA | |
| SCHEMBL29123324 | 0.86 | LTA4H (0.54) | SCN9AMAPK1FFAR1LTA4HGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |