SCHEMBL29123711

SCHEMBL29123711

CC(C)(C)NC(=O)O[C@@H](CO)CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.38
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28687703 1.00 PRKCA (0.38) PRKCASCN9A
SCHEMBL28551621 0.85 PRKCA (0.30) PRKCA
SCHEMBL28692700 0.80 PRKCA (0.44) PRKCA
SCHEMBL28965205 0.80 PRKCA (0.44) PRKCA
SCHEMBL28487635 0.80 PRKCA (0.41) PRKCA
SCHEMBL28487634 0.80 PRKCA (0.41) PRKCA
SCHEMBL18343881 0.78
SCHEMBL18343770 0.76 PRKCA (0.38) PRKCA
SCHEMBL29273401 0.75 PRKCA (0.38) PRKCA
SCHEMBL29271806 0.74 PRKCA (0.37) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117015537-A Heteroaryl aminopropanol derivatives as inhibitors of LTA4H 诺华股份有限公司 2023-11-07 CN disclosed