Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487634 | 1.00 | PRKCA (0.41) | PRKCAPRKCEPRKCQPRKCDCHRM2 | |
| SCHEMBL28671166 | 0.84 | PRKCA (0.33) | PRKCA | |
| SCHEMBL28671165 | 0.84 | PRKCA (0.33) | PRKCA | |
| SCHEMBL28687703 | 0.80 | PRKCA (0.38) | PRKCA | |
| SCHEMBL29123711 | 0.80 | PRKCA (0.38) | PRKCA | |
| SCHEMBL28720019 | 0.78 | LMNA (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28960244 | 0.78 | LMNA (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28720018 | 0.78 | LMNA (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2176554 | 0.77 | PRKCA (0.32) | PRKCA | |
| SCHEMBL3519542 | 0.77 | CYP2C9 (0.38) | PRKCACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-115209955-A | Compounds for the treatment of familial autonomic nerve dysfunction | PTC医疗公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-113795304-A | Thieno [3,2-B ] pyridin-7-amine compounds for the treatment of familial autonomic nervous dysfunction | PTC医疗公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-111936484-A | Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase | 拉文纳制药公司 | 2020-11-13 | — | — | CN | disclosed |