Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123777 | 1.00 | LTA4H (0.51) | LTA4HKCNH2SCN9AACACBMAPT | |
| SCHEMBL29123730 | 0.91 | LTA4H (0.42) | LTA4HKCNH2SCN9AMAPTTP53 | |
| SCHEMBL29123726 | 0.91 | LTA4H (0.42) | LTA4HKCNH2SCN9AMAPTTP53 | |
| SCHEMBL29123608 | 0.87 | LTA4H (0.52) | LTA4HKCNH2SCN9AMAPTMITF | |
| SCHEMBL29123605 | 0.87 | LTA4H (0.52) | LTA4HKCNH2SCN9AMAPTMITF | |
| SCHEMBL29123393 | 0.87 | SCN9A (0.54) | LTA4HKCNH2SCN9ALMNAFFAR1 | |
| SCHEMBL29123397 | 0.87 | SCN9A (0.54) | LTA4HKCNH2SCN9ALMNAFFAR1 | |
| SCHEMBL27171420 | 0.85 | LTA4H (0.68) | LTA4HKCNH2SCN9AACACBMAPT | |
| SCHEMBL27204783 | 0.85 | LTA4H (0.68) | LTA4HKCNH2SCN9AACACBMAPT | |
| SCHEMBL30731710 | 0.84 | LTA4H (0.44) | LTA4HKCNH2SCN9AACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |