Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123393 | 1.00 | SCN9A (0.54) | SCN9ALTA4HFPR2LMNAFFAR1 | |
| SCHEMBL29123469 | 0.90 | SCN9A (0.46) | SCN9ALTA4HFPR2FFAR1 | |
| SCHEMBL29123473 | 0.90 | SCN9A (0.46) | SCN9ALTA4HFPR2FFAR1 | |
| SCHEMBL30731680 | 0.89 | SCN9A (0.53) | SCN9ALTA4HFPR2LMNAFFAR1 | |
| SCHEMBL29123607 | 0.88 | SCN9A (0.49) | SCN9ALTA4HFPR2LMNAFFAR1 | |
| SCHEMBL29123780 | 0.87 | LTA4H (0.51) | SCN9ALTA4HFPR2LMNAFFAR1 | |
| SCHEMBL29123777 | 0.87 | LTA4H (0.51) | SCN9ALTA4HFPR2LMNAFFAR1 | |
| SCHEMBL29123608 | 0.86 | LTA4H (0.52) | SCN9ALTA4HFPR2FFAR1KCNH2 | |
| SCHEMBL29123605 | 0.86 | LTA4H (0.52) | SCN9ALTA4HFPR2FFAR1KCNH2 | |
| SCHEMBL27171402 | 0.85 | LTA4H (0.67) | SCN9ALTA4HFPR2LMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |