Pyrrole

Pyrrole

SCHEMBL29124170

B.FC#Cc1ccccc1.c1cc[nH]c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.46
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
THPO P40225 1/20 0.40
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
MAPT P10636 3/20 0.37
FFAR1 O14842 2/20 0.36
GRM5 P41594 2/20 0.35
HTR2A P28223 1/20 0.34
ASIC3 Q9UHC3 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
NPC1 O15118 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208030 0.83
Alcohol SCHEMBL28009111 0.76 APP (0.48) APPCYP1A2CYP3A4CYP2C9CYP2C19
Pyrrole SCHEMBL28829087 0.75 APP (0.42) APPCYP1A2CYP3A4CYP2C9CYP2C19
Benzonitrile SCHEMBL27804422 0.70 TSHR (0.70) APPMAPTNPC1ALDH1A1SMN1; SMN2
Diphenylacetylene SCHEMBL28768551 0.69 APP (0.92) APPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL718611 0.69 APP (0.42) APPCYP1A2MAPTFFAR1
Fluorobenzene SCHEMBL28280173 0.69 NFE2L2 (0.39) ALDH1A1KMT2ASMN1; SMN2RAB9A
SCHEMBL205838 0.68
Benzene SCHEMBL28136930 0.68 APP (0.65) APPCYP1A2CYP3A4CYP2C9CYP2C19
Diphenylether SCHEMBL29176055 0.67 LTA4H (0.63) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835739-B Disubstituted phenylethynyl fluorine boron pyrrole fluorescent dichromatic liquid crystal compound and application thereof 大连理工大学 2023-11-10 CN claimed
CN-114835739-B Disubstituted phenylethynyl fluorine boron pyrrole fluorescent dichromatic liquid crystal compound and application thereof 大连理工大学 2023-11-10 CN disclosed
CN-114835739-B Disubstituted phenylethynyl fluorine boron pyrrole fluorescent dichromatic liquid crystal compound and application thereof 大连理工大学 2023-11-10 CN disclosed
CN-114835739-B Disubstituted phenylethynyl fluorine boron pyrrole fluorescent dichromatic liquid crystal compound and application thereof 大连理工大学 2023-11-10 CN disclosed