SCHEMBL29124288

SCHEMBL29124288

CC/C(=C/CC(=O)O)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.41
ALDH1A1 P00352 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX15 P16050 1/20 0.38
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026399 0.87 FFAR3 (0.47) FFAR3ALDH1A1CYP2D6ALOX15TDP1
SCHEMBL7641786 0.85 ALOX15 (0.45) ALDH1A1CYP2D6ALOX15LDHASRR
SCHEMBL6026397 0.83 FFAR3 (0.43) FFAR3ALDH1A1ALOX15LDHASRR
SCHEMBL8539187 0.83 FFAR3 (0.43) FFAR3ALDH1A1ALOX15LDHASRR
Ammonia Solution, Strong SCHEMBL1969561 0.82 ALOX15 (0.43) ALDH1A1CYP2D6ALOX15LDHASRR
SCHEMBL10779589 0.77
SCHEMBL868460 0.77
SCHEMBL868459 0.77
SCHEMBL26674024 0.76 AKR1B1 (0.43) ALDH1A1ALOX15TDP1TSHR
SCHEMBL5506993 0.73 FFAR3 (0.50) FFAR3ALDH1A1CYP2D6ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117202901-A Use of citraconic acid and its derivatives as medicaments 亥姆霍兹感染研究中心有限公司 2023-12-08 CN disclosed