Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641786 | 0.97 | ALOX15 (0.45) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL29124288 | 0.82 | FFAR3 (0.41) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL27563695 | 0.72 | LDHA (0.42) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL6026399 | 0.72 | FFAR3 (0.47) | ALOX15ALDH1A1CYP2D6TSHR | |
| SCHEMBL4887355 | 0.70 | TSHR (0.54) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL19407227 | 0.70 | TSHR (0.54) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL22688958 | 0.70 | ALOX15 (0.41) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL13541377 | 0.70 | TSHR (0.54) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL27361335 | 0.70 | ALOX15 (0.41) | ALOX15ALDH1A1CYP2D6LDHASRR | |
| SCHEMBL8757965 | 0.70 | ALOX15 (0.41) | ALOX15ALDH1A1CYP2D6LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840858-A | Protein purification using immobilized metal affinity chromatography for complement receptor proteins | T CELL SCIENCES, INC. (US) | 1998-11-24 | — | — | US | claimed |
| US-5409677-A | Process for separating a radionuclide from solution | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1995-04-25 | — | — | US | claimed |
| US-12472448-B2 | Compact hydroxamate-based affinity tags for artificially tagging biological macromolecules | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-11-18 | — | — | US | disclosed |
| US-20250321207-A1 | Chromatography | NOVA PRIMARY MANUFACTURING LTD (GB) | 2025-10-16 | — | — | US | disclosed |
| US-12403461-B2 | Solid-phase chelator material, method for producing thereof and use thereof for the purification of proteins | CUBE BIOTECH GMBH (DE) | 2025-09-02 | — | — | US | disclosed |
| EP-3887033-B1 | SOLID-PHASE CHELATOR MATERIAL, METHOD FOR PRODUCING THEREOF AND USE THEREOF FOR THE PURIFICATION OF PROTEINS | CUBE BIOTECH GMBH (DE) | 2024-07-24 | — | — | EP | disclosed |
| US-11884701-B2 | Chromatography membranes, devices containing them, and methods of use thereof | MERCK MILLIPORE LTD. (IE) | 2024-01-30 | — | — | US | disclosed |
| EP-3427815-B1 | DEVICE WITH LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY | MERCK MILLIPORE LTD (IE) | 2023-12-06 | — | — | EP | disclosed |
| US-20220054955-A1 | COMPACT HYDROXAMATE-BASED AFFINITY TAGS FOR ARTIFICIALLY TAGGING BIOLOGICAL MACROMOLECULES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-02-24 | — | — | US | disclosed |
| US-20220023851-A1 | SOLID-PHASE CHELATOR MATERIAL, METHOD FOR PRODUCING THEREOF AND USE THEREOF FOR THE PURIFICATION OF PROTEINS | CUBE BIOTECH GMBH (DE) | 2022-01-27 | — | — | US | disclosed |
| US-11208444-B2 | BRCA2-mediated purification of recombinase protein | Idea Seed, LLC. (US) | 2021-12-28 | — | — | US | disclosed |
| WO-2008124015-A1 | METHODS FOR PURIFYING ADENO-ASSOCIATED VIRUS VIRIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20080158558-A1 | Phosphopeptide detection and surface enhanced Raman spectroscopy | INTEL CORPORATION | 2008-07-03 | — | — | US | disclosed |
| WO-2007095201-A2 | PSEUDOTYPED RETROVIRAL VECTORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |
| US-7176298-B2 | Polynucleotides encoding metal ion affinity peptides and related products | CLONTECH LABORATORIES, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| US-20060030007-A1 | Peptides for metal ion affinity chromatography | Life Technologies Corporation | 2006-02-09 | — | — | US | disclosed |
| WO-2004106361-A2 | PEPTIDES FOR METAL ION AFFINITY CHROMATOGRPAHY | INVITROGEN CORPORATION (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040180415-A1 | Methods and compositions for protein purification | CLONTECH LABORATORIES, INC. | 2004-09-16 | — | — | US | disclosed |
| US-20020164718-A1 | Metal ion affinity tags and methods for usig the same | TAKARA BIO USA, INC. | 2002-11-07 | — | — | US | disclosed |
| US-5409677-A | Process for separating a radionuclide from solution | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1995-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220023851-A1 | SOLID-PHASE CHELATOR MATERIAL, METHOD FOR PRODUCING THEREOF AND USE THEREOF FOR THE PURIFICATION OF PROTEINS | SRM, PDAP1, DNPEP | ALOX15 4149/4885ALDH1A1 4023/4885CYP2D6 4848/4885 |
| US-12403461-B2 | Solid-phase chelator material, method for producing thereof and use thereof for the purification of proteins | SRM, PDAP1, DNPEP | ALOX15 4149/4885ALDH1A1 4023/4885CYP2D6 4848/4885 |
| US-12472448-B2 | Compact hydroxamate-based affinity tags for artificially tagging biological macromolecules | HLCS, AADAC, HYPK | ALOX15 4738/4885ALDH1A1 3867/4885CYP2D6 4726/4885 |
| US-20220054955-A1 | COMPACT HYDROXAMATE-BASED AFFINITY TAGS FOR ARTIFICIALLY TAGGING BIOLOGICAL MACROMOLECULES | HLCS, AADAC, HYPK | ALOX15 4738/4885ALDH1A1 3867/4885CYP2D6 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.