Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL29021088 | 0.92 | MGAM (0.43) | MAPTTSHRALDH1A1TDP1ALOX15 | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL28299898 | 0.86 | MGAM (0.44) | MAPTTSHRALDH1A1TDP1SLC22A6 | |
| SCHEMBL76382 | 0.86 | — | — | |
| SCHEMBL434191 | 0.86 | — | — | |
| SCHEMBL54111 | 0.86 | — | — | |
| SCHEMBL2046528 | 0.85 | ALDH1A1 (0.47) | AKR1B1MAPTGPR84PPARGPPARD | |
| SCHEMBL27668114 | 0.84 | MGAM (0.50) | MAPTTSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL27522306 | 0.84 | — | — | |
| SCHEMBL727456 | 0.83 | TSHR (0.41) | AKR1B1MAPTTSHRALDH1A1FFAR1 | |
| SCHEMBL20798165 | 0.83 | TSHR (0.41) | AKR1B1MAPTTSHRALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917264-A | Process for preparing hydroxybutyric acid carboxylic ester | 凯托利皮克斯治疗有限责任公司 | 2023-10-20 | — | — | CN | disclosed |