Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124728 | 0.83 | BTK (0.53) | BTKLCKEPHX2 | |
| SCHEMBL29124706 | 0.83 | BTK (0.51) | BTKSMN1; SMN2EPHX2 | |
| SCHEMBL29124856 | 0.82 | BTK (0.45) | BTKLCKSMN1; SMN2 | |
| SCHEMBL29124637 | 0.80 | BTK (0.41) | BTKEPHX2 | |
| SCHEMBL17645703 | 0.78 | BTK (0.46) | BTKLCKEPHX2 | |
| SCHEMBL23303632 | 0.76 | BTK (0.49) | BTKLCK | |
| SCHEMBL25649398 | 0.76 | BTK (0.46) | BTKLCK | |
| SCHEMBL19876263 | 0.75 | BTK (0.60) | BTKLCK | |
| SCHEMBL22664846 | 0.75 | BTK (0.51) | BTKLCK | |
| SCHEMBL29124777 | 0.75 | BTK (0.39) | BTKEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |