Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125986 | 0.88 | ALOX15 (0.34) | ALOX15MAPTNISCHKMT2AHSD17B10 | |
| SCHEMBL29125777 | 0.80 | TSHR (0.44) | TSHRTACR1KMT2AALDH1A1LMNA | |
| SCHEMBL29125698 | 0.78 | DAO (0.39) | TSHRTACR1ALDH1A1GLAKDM4E | |
| SCHEMBL29126060 | 0.77 | BRS3 (0.36) | TSHRBRS3KMT2AHSD17B10GLA | |
| SCHEMBL29125740 | 0.76 | KMT2A (0.36) | TSHRTACR1MAPTKMT2AHSD17B10 | |
| SCHEMBL29125836 | 0.76 | TSHR (0.36) | TSHRTACR1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL29125687 | 0.76 | TSHR (0.44) | TSHRALOX15NISCHKMT2AHSD17B10 | |
| SCHEMBL29125763 | 0.74 | TSHR (0.39) | TSHRKMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL29125936 | 0.74 | LMNA (0.40) | TSHRKMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL29125839 | 0.74 | KMT2A (0.40) | TSHRBRS3TACR1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |