Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125992 | 0.87 | ALDH1A1 (0.44) | MTNR1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29126046 | 0.83 | NOTUM (0.43) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL29125890 | 0.82 | NOTUM (0.46) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL29125875 | 0.81 | NOTUM (0.42) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL29125749 | 0.80 | SORT1 (0.38) | MTNR1BNOTUMMTNR1ASORT1ALDH1A1 | |
| SCHEMBL29125835 | 0.80 | NOTUM (0.36) | MTNR1BNOTUMMTNR1ASORT1 | |
| SCHEMBL29125696 | 0.75 | ALDH1A1 (0.50) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL30788512 | 0.75 | ALDH1A1 (0.50) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL29125914 | 0.75 | SORT1 (0.40) | MTNR1BNOTUMMTNR1ASORT1KDM4E | |
| SCHEMBL29128317 | 0.75 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |