Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125939 | 0.88 | ALDH1A1 (0.52) | KDM4EALDH1A1LMNAPOLBTP53 | |
| SCHEMBL29125689 | 0.80 | NOTUM (0.40) | KDM4EALDH1A1LMNANOTUMDAO | |
| SCHEMBL29128195 | 0.77 | MAPT (0.32) | KDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL29125798 | 0.76 | NOTUM (0.37) | NOTUMDAOPTGS1MTNR1B | |
| SCHEMBL29125934 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNANOTUMPTGS1 | |
| SCHEMBL29125923 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL29125790 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNANOTUMSYK | |
| SCHEMBL29125744 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNANOTUMHTT | |
| SCHEMBL29125727 | 0.73 | MTNR1B (0.37) | ALDH1A1NOTUMPTGS1MTNR1BMTNR1A | |
| SCHEMBL29125916 | 0.73 | ALDH1A1 (0.63) | KDM4EALDH1A1LMNANOTUMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |