Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125718 | 0.88 | TSHR (0.46) | KDM4EALDH1A1TSHRMTNR1AMTNR1B | |
| SCHEMBL29125808 | 0.85 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL29125804 | 0.79 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL29125801 | 0.78 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL29125983 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2TSHRGAA | |
| SCHEMBL29125781 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2TSHRMMP13 | |
| SCHEMBL29125902 | 0.75 | KDM4E (0.32) | KDM4EALDH1A1TSHRMMP13KMT2A | |
| SCHEMBL29125786 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL29125776 | 0.74 | NPC1 (0.34) | SMN1; SMN2MAPK1L3MBTL1GAAKMT2A | |
| SCHEMBL29125694 | 0.70 | RAB9A (0.51) | ALDH1A1SMN1; SMN2TSHRGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |